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GSK

Cell Biologist - 1 year Fixed Contract

A one year opportunity has become available for a for a highly motivated cell biologist within the Department of Screening, Profiling & Mechanistic Biology (SPMB) at GSK's Medicines Research Centre in Stevenage. The department is responsible for broad biological activities predominantly in the pre-clinical drug discovery space, including assay development, compound profiling and mechanism of action studies. Scientists within the department work in close collaboration with colleagues from multiple research areas to define our drug discovery and screening strategies, and in doing so help establish and maintain awareness of the target and therapeutic rational across the programs we support.
We can offer;
• Exposure to novel cell assay platforms and technologies
• Exposure to the early-phase assay portfolio across a number of research areas
• Practicalities and processes for the generation, QC and delivery of highly impactful assays and data to discovery project teams
• Application of automation to enable delivery of complex/advanced cell biology data

Applicant Skills Sought -
• A bench facing scientist looking to impact early-phase discovery programs
• The candidate should be able to demonstrate broad practical experience with cell assay systems and a track record of leading and influencing scientific research in this area
• Experience in the design and development of mechanistic cell based assays, across multiple cell types and utilising multiple technologies
• Has worked with advanced/complex cellular systems (e.g. primary cells, co-cultures, stem cells, 3D cell culture, tissue samples).
• The application of functional genomic screening would be an advantage (si-/shRNA and/or CRISPR-Cas9).

Training Provided
• Application of cell biology expertise to new areas and in advanced/complex cellular systems
• Develop skills with advanced multi-parametric cellular detection systems such as high-content imaging, flow cytometry, high-throughput sandwich immunoassays etc.
• Learn about the scaling of biological assays for screening approaches in support of the R&D portfolio (including assay automation, QC and downstream data analysis, etc)
• Broaden awareness of early phase discovery projects with the opportunity to interact with discovery research programme teams.
• Exposure to and close interactions with other departments that support early-phase deliverables.

CLOSING DATE for applications: 8th March 2019 (COB)

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements please contact 0808 234 4391. This will help us to understand any modifications we may need to make to support you throughout our selection process.

Why You?Basic qualifications:
• A bench facing scientist looking to impact early-phase discovery programs
• The candidate should be able to demonstrate broad practical experience with cell assay systems and a track record of leading and influencing scientific research in this area
• Experience in the design and development of mechanistic cell based assays, across multiple cell types and utilising multiple technologies

Preferred qualifications:
• Has worked with advanced/complex cellular systems (e.g. primary cells, co-cultures, stem cells, 3D cell culture, tissue samples).
• The application of functional genomic screening would be an advantage (si-/shRNA and/or CRISPR-Cas9).

Why GSK?:
GlaxoSmithKline is a science-led global healthcare company that researches and develops a broad range of innovative medicines and brands. We discover, make and market life-enhancing products that are used by millions of people around the world, helping them to do more, feel better and live longer. We have 3 primary areas of business in pharmaceuticals, vaccines and consumer healthcare. We have offices in more than 115 countries, major research centers in the UK, USA, Spain, Belgium and China and an extensive manufacturing network with 87 sites globally. Our three strategic priorities are to grow a diversified global business, deliver products of value, and to simplify our operating model.

Contact information:
You may apply for this position online by selecting the Apply now button.

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