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PPD

Research Scientist - Cellular Immunology

PPD is a leading global contract research organization providing comprehensive, integrated drug development, laboratory and lifecycle management services.  At PPD, we are passionate, deliberate, and driven by our purpose- to improve health!   

Envision a workplace where you have a direct impact on improving health, work alongside expert scientists, use newest technologies and collaborate with industry thought leaders and therapeutic experts. Welcome to PPD® Laboratories, where science is our passion, quality is our commitment and people are the cornerstone of our success.  


PPD Laboratories offers the most comprehensive set of laboratory services available in the industry and continues to deliver innovative solutions to our clients through our collaborative approach, including PPD Laboratories FSP. PPD Laboratories FSP is a unique partnership that allows our clients to leverage the experience of our PPD staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits/advantages of being a part of PPD.


As a Research Scientist you will conduct and provide technical guidance on scientific method development and validation projects and/or other specialty technologies studies OR perform troubleshooting for your own and others instruments, methods, procedures, and in write protocols and reports.  

 

Responsibilities


Key member of diverse team of vaccine scientists to develop animal models and immunologic assays to screen and evaluate the potency, safety and the mechanisms of action of vaccine candidates and to support platform technology development.


Has in depth knowledge of related scientific disciplines in particular advanced knowledge of immunology principles, vaccine-related innate and adaptive immune responses and mechanism of action of vaccines.


Hands-on lab experience in performing all kinds of immunological assays with a focus on cellular immunology assays such as characterization of vaccine specific T-cell and B-cell subsets and innate immune cells by intracellular cytokine staining (ICS) and multi-parameter flow cytometry (FACS) etc. as they apply to vaccine discovery/development.


Proficient in analysis of complex high dimensional flowcytometry data using FlowJo, R program, Spice, Pestle etc. and use of GraphPad (Prism), SAS, Microsoft Office tools and other software.


Experienced in performing preclinical in vivo animal vaccine studies in mice, NHP and other animal models and analysis of immune cells from various tissues. Prior experience in working with CRO’s is preferred.


Interprets results and communicates to his/her supervisor and/or designs next logical step of experiments based on interpretation of results. 


Executes a range of experiments/technical studies/tasks independently based on protocol including animal vaccine studies, ICS, FACS, antibody assays etc. to evaluate vaccine immunogenicity.


Designs and executes new methods and protocols related to area of expertise and/or proactively incorporates new technology or techniques into practice with minimal supervision.


Prepares detailed oral or written summaries of results with interpretation for projects/programs. Independently writes specific technical sections of internal, external reports and scientific papers



PPDFSP

Education and Experience

  • Bachelors degree and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable 8 years)

OR

  • Masters and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable 6 years)

 

Knowledge, Skills and Abilities

 

Previous Experience Requirement:


Cellular immunology assays including multi-parametric flow cytometry analysis, tissue culture and experience with high-throughput assays


Contributing information and data as required and ensuring accuracy of data provided and timely sharing of data


Understands and follows work instructions and/or standard protocols and procedures


Understands scientific presentations by team members required for own job activities


Understands and applies job-relevant PPD / client processes, timelines and resource management


Understands standard operating procedures and internal policies required to maintain quality standards and to protect PPD / client intellectual property


Has in depth knowledge of related scientific disciplines in particular advanced knowledge on immunology principles especially on vaccine-related adaptive immune responses.


Hands-on lab experience in performing all kinds of immunological assays with a focus on cellular immunology assays such as characterization of vaccine specific T-cell and B-cell subsets and innate immune cells by intracellular cytokine staining (ICS) and multi-parameter flow cytometry (FACS) etc. as they apply to vaccine discovery/development.


Proficient in analysis of complex flowcytometry data using FlowJo, R program, Spice, Pestle, Graphpad (Prism), SAS, Microsoft Office tools and other software.


Experienced in performing preclinical in vivo animal vaccine studies in mice, NHP and other animal models and analysis of immune cells from various tissues.


Prior experience in working with CRO’s is preferred.


Proven problem solving and troubleshooting abilities


Proven ability in technical writing skills


Time management and project management skills


Good written and oral communication skills


Ability to work in a collaborative work environment with a team


Ability to train junior staff

 

PPD values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive.  Below is listed the working environment/requirements for this role:


Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.

Able to work upright and stationary and/or standing for typical working hours.

Able to lift and move objects up to 25 pounds

Able to work in non-traditional work environments.

Able to use and learn standard office equipment and technology with proficiency.

May have exposure to potentially hazardous elements including infectious agents typically found in healthcare or laboratory environments.

Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.  

 

 

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